Tuesday, January 10, 2012

Can antibodies enter cells?

Antibodies are proteins, which to me suggest they are far too big to p through the plasma membrane. However, I was reading about fluorescence microscopy, and it says that antibodies for a certain cellular protein that you want to see (such as a neurofilament say) are attached to fluorescent markers (making them even bigger!) where they bind to the relevant protein in the cell. But how did they get in there?

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